TARGETING N-GLYCAN CRYPTIC SUGAR MOIETIES FOR BROAD-SPECTRUM VIRUS NEUTRALIZATION: PROGRESS IN IDENTIFYING CONSERVED MOLECULAR TARGETS IN VIRUSES OF DISTINCT PHYLOGENETIC ORIGINS

Identifying molecular targets for eliciting broadly virus-neutralizing antibodies is one of the key steps toward development of vaccines against emerging viral pathogens.Owing to genomic and somatic diversities among viral species, identifying protein targets for broad-spectrum virus neutralization is highly challenging even for the same virus, suc

The aim of present investigation deals with the development of time-dependent and pH sensitive press-coated tablets for colon specific drug delivery of naproxen.The core tablets were prepared by wet granulation method then press coated with hydroxypropyl cellulose (HPC) or Eudragit RSPO : RLPO mixture and further coated with Eudragit S-100 by dip i

Various symptoms emerge as immune-related adverse events of immune checkpoint inhibitor (ICI).A 73-year-old woman, Shakers a non-smoker, receiving chemotherapy including atezolizumab for lung adenocarcinoma, presented with fever, bilateral parotid swelling and sicca syndrome after four courses of chemotherapy.Because the lesions were not localized,

Abstract Background A hip joint ganglion is a rare cause of lower-extremity swelling.Case presentation We report a case of a Japanese patient with ganglion of the hip with compression of the external iliac/femoral vein that produced signs and Room Mist symptoms mimicking those of deep vein thrombosis.Conclusions Needle aspiration of the ganglion wa